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Services

API Synthesis Facilities

The planning and realization of a modern plant for the production of APIs (Active Pharmaceutical Ingredients) is more than ever a complex task in which problems from the most diverse areas have to be solved. This applies not only to the construction of new production plants - whether multipurpose or mono plants - but also to the conversion or repurposing of existing facilities and the necessary infrastructure systems, e.g. for the generation of ultra-pure media or waste gas treatment.

Thanks to a structured and methodical approach, we can determine your individual requirements and implement them precisely. We work closely with you in all planning phases to determine the essential information on the manufacturing process and product requirements. Our experts have in-depth knowledge in all relevant specialist areas and bring the experience of many successfully implemented projects to you.

 

"Invented Here" is no longer in

The know-how about the manufacturing process and the specific product requirements usually lies with the operator, who has developed the synthesis process and sells the product himself or has it sold. However, the implementation of an investment project requires experience and skills from many different disciplines, which are often not (or no longer) sufficiently available in the manufacturing industry today. In most cases, planning begins with the process and the technical equipment required for it.

What is not directly part of this, e.g. energy supply, waste disposal facilities, sometimes also questions of safety and occupational hygiene, are usually treated rather neglected in the early project phase and lag behind the planning progress, although these aspects are just as important. When it comes to important milestones, it is precisely these planning results and reliable information that are missing in order to make fundamental decisions. Not infrequently, there is also a certain blinkered thinking within the company, which benefits from fresh impetus from outside.

 

Consult specialists at an early stage

The project initiation and concept phase requires an energetic team of experienced experts to tackle all relevant aspects and issues in an environment that encourages creativity. Depending on the available personnel resources of the investing company, it is sensible and expedient to call in external support for individual special topics or for the entire project. Chemgineering has already carried out such assignments for various renowned customers.

We either make individual specialists available as consultants for subtasks, or Chemgineering takes the lead and integrates the customer's specialists into its own project team. In this way, we ensure that not only the process-related problems are addressed, but also all other relevant aspects.

Our experts have in-depth, tried-and-tested knowledge in all key disciplines and specialist areas: Process engineering, biotechnology, sterile technology, I&C and electrical engineering, clean room technology, ultra-pure media, safety technology, etc.

Speaking the same language, thinking entrepreneurially

Chemgineering has a methodical approach in which its requirements are determined and described in close cooperation with the future operator.

A major advantage is that some of our seniors used to work "on the other side" and therefore speak the language of chemists and operators and understand their needs. On the other hand, we have sufficient entrepreneurial thinking skills to be able to evaluate requirements and wishes from an economic point of view.

By focusing on a limited industry segment in particular, we can exploit the synergies that arise from processing orders for pharmaceuticals, fine chemicals, vitamin production or diagnostics. This gives us a broad overview of proven technical solutions that we can adapt to new problems. The handling of highly potent substances, whose production share is increasing due to the ever-increasing effectiveness of pharmaceuticals, is a current topic in this context.

We know what your API facility is all about

We have acquired the know-how that we bring to bear in the preliminary planning phases through the successful realization of many investment projects. Our project engineers, who are deployed in concept planning or basic engineering, are generally also responsible for commissioning the systems. This motivates them to teach their "baby" to run. The experience gained flows into the next planning phase.

Good ideas and cost-effective solutions are worth nothing without professional project management and efficient tools - especially when it comes to detailed planning, which we carry out using modern 3D CAD tools as well as conventional methods. Chemgineering has a unique selection of technical experts and generalists who are highly motivated to turn your ideas and requirements into modern and economical systems that comply with the applicable rules and regulations.

We plan your API synthesis facility

and coordinate the professional implementation of:

  • Production of active ingredients
  • Highly potent drugs
  • Biotechnology
  • Process engineering
  • Infrastructure facilities
  • GMP upgrades
  • Safety
  • Environmental protection
  • Process simulation
  • Process development
  • Project management

Relevant Projects

Expansion of Production by Two Glass-lined Reactors
New Facility HD15
F/3000 DSP Cystine León
Recombinant Ebola Vaccine Production
Requalification of a Vitamin Production Plant
Conversion of a multi-purpose system for HAPI operation
Esteve Química
Pharmachem
Sintenovo
Building 50 MZ 170

If you have any questions about API synthesis facilities, please contact us

We help you to successfully implement your project.

With professionally planned API synthesis facilities.

Switzerland +41 (0) 61 467 54 00
Germany +49 (0) 611 778870
Spain +34 (0) 932 38 49 90