CAD-Supported Plant Design

Planning of two glass-lined reactors, including all connections for steam, air, cooling water, exhaust air, vacuum, nitrogen.

Centrifuge plant. Upgrade of a cone Dryer, GMP cabin for big bag filling

Green field production of chemicals: Process euipment, process and building services, utilities and clean rooms.

Planning and execution of a new plant (4 floors) for the production of natural products under high pressure conditions (supercritical CO₂ up to 1,000 bar).

New building for the production and packaging of solid dosage forms and inhalation products.

Planning of a filling line for pre-filled syringes in Switzerland, including planning of all process systems and building infrastructure through to commissioning.

Planning of a plasma fractionation with 650,000 l / 1 million l (expansion) per year; basic fractionation, purification, fill & finish, products: IVIG, albumin, FVIII, each in different concentrations. Planning as a "sandwich concept", production-centered arrangement with the supply below and HVAC above.

Planning of a production plant for endoglycosiadases (and in future also mRNA). Microbiological plant (yeasts and bacteria) with 30l / 300l (after expansion) fermentation volume. Planning as a classic upstream-downstream plant with single-use technology for fermentation and purification.

New planning of standard laboratories, extension of 2^nd floor of an existing laboratory building during ongoing production.

Cell therapy laboratory with various clean room zones incl. storage/logistics and technical areas. Development of the user requirements and the optimum room concept in close cooperation with six different user groups (different processes / laboratory requirements). Total area of 1,000m².

Downstream process for the production of cystine powder.

Conversion of a production facility, USP and DSP, for cell culture-based vaccine production, including adaptation of media, clean rooms, HVAC and chemical wastewater inactivation.

Design of a new laboratory, microbiology laboratory, extension of an existing building during ongoing production.

Planning, execution and commissioning of GMP production rooms and laboratories including process media.

New offices and laboratories for research and development.

New research and development laboratories and new offices.

Two-storey refurbishment in an office building. Updated and customized design for offices, showrooms, laboratories, meeting rooms and services.

Feasibility study for conversion of existing personnel and material locks, filling and packaging lines, conveyor technology.

Facility for the production of blisters for medical products.

Renovation of old building and planning of new building. Concept study of old building and new building for Pharmaceuticals, diagnostics, cosmetics.

Disposal of solvent-containing exhaust air, 12`000 Nm3/h Regenerat. therm. Oxidation (RTO): Process and source exhaust air, exhaust air from waste water treatment plant and industrial waste water systems.

Fine chemicals multi-purpose plant with stirred tank, centrifuge, dryer, rectification, (corrosion-resistant).

Production plant for the manufacture of neodymium catalysts.

Development of a new primary packaging material for parenteral application.

GMP-compliant conversion of plasma processing (10,000 m²) incl. PM for new sterile filling.

Evaluation & preliminary planning of technical and organizational measures for the operation of an existing multi-purpose facility with highly active substances.

New API production plant, new production facilities, new research center, offices, warehouse and logistics center.

Construction of a production building for APIs and intermediates; 100 m³ reaction capacity, batch process.

Multi-purpose plant for the production of final & finishing steps for active pharmaceutical ingredients 3 HC-22 reactors of 6.3 m³ each, HC-22 centrifuge, infrastructure.

Planning of a new FFF line, incl. construction and complete building services (HVAC + EMSR).

Concept design and engineering for a new production facility for cell therapies on an area of 1,000 m² (brownfield). Production of dendritic cells, CAR-T cells and lentiviral vectors. Main features: Flexible production - cell suites, production area for lentiviral vectors, QC labs, storage, cold chain management.

Procurement of new PW generators, adaptation of automation incl. connection to BMS + MAS, dismantling of existing generators.

Production plant for the manufacture of animal feed.

New construction of a factory for the production of food supplements; microbial fermentation, DSP, media & infrastructure.

Laboratory for cell and gene therapy, total area approx. 1800 m². Process transfer USA - Switzerland.

Design of a modular and standardized production line for cosmetic products. The production line was integrated into an existing building at the site.